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So far, research suggests that Botox injections for ED are generally safe and well-tolerated, with only a few mild side effects reported.[5]Commonly observed effects include: Mild pain or soreness at the injection site Occasional local skin reaction (such as slight redness or irritation) Temporary dribbling or weaker erections, which usually go away on their own Short-lived results, typically lasting about three months Unknown long-term safety, as larger studies are still needed Importantly, no serious side effects such as priapism (a prolonged erection) or overall toxicity were reported in studies

Tesar A, Matej R, Kukal J, Johanidesova S, Rektorova I, Vyhnalek M, Keller J, Eliasova I, Parobkova E, Smetakova M, Musova Z, Rusina R (2019) Clinical variability in P102L GerstmannStrusslerScheinker Syndrome