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If improvement is not observed after appropriate dosage adjustment over a 1-month period, the drug should be discontinued 2 If switching from other methylphenidate products to QuilliChew ER: Discontinue that treatment and titrate with QuilliChew ER using the above titration schedule Do not substitute for other methylphenidate products on a milligram-per-milligram basis because of different methylphenidate base compositions and differing pharmacokinetic profiles Writing a prescription for QuilliChew ER Example prescription When prescribing multiple dosage strengths of QuilliChew ER with different NDCs when 1 dosage strength could be used to fill the prescription, it is important to remember: This may result in additional out-of-pocket or co-pay costs for your patients Insurance may cover a prescription for multiple strengths within one 30-day time frame