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Recently, our group also showed that HSPA9/mortalin depletion induces pexophagy by increasing peroxisomal ROS 74
[ 438 , 439 ] Sickle cell disease (SCD) is initiated as consequence of a point mutation in the globin chain of hemoglobin, which leads to a substitution of valine for glutamate at position 6, manifesting as chronic hemolytic anemia
