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Orally, vitamin E has been studied for the use in a large variety of conditions, such as: Cardiovascular disease Diabetes Liver disease Kidney disease Cancer Offsetting the adverse effects of chemotherapy Slowing the onset of Alzheimers disease and other dementias Parkinsons disease Night cramps Restless leg syndrome (RLS) Epilepsy Improving physical endurance and energy Allergies Asthma Respiratory infections Protecting against the negative effects of air pollution Cataracts and age-related macular degeneration Inflammatory skin disorders Aging skin Sunburns Cystic fibrosis Oral leukoplakia Premenstrual syndrome (PMS) Depression Menopausal syndrome Benign breast disease Osteoporosis Infertility Impotence Chronic fatigue syndrome (CFS) Amyotrophic lateral sclerosis (ALS) H

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Nowith 170mg of caffeine per serving, it's not recommended within 6 hours of sleep as it may interfere with rest and recovery.