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Singh P, Pandit S, Balusamy SR, Madhusudanan M, Singh H, Amsath Haseef HM, et al

Anti-inflammatory effects Acne is largely driven by inflammation

0.25mg/kg x 6 kg = 1.5mg and 0.5mg/kg x 6 kg = 3 mg Total dose of prednisone = 1.5- 3mg Total dose of methylprednisolone= 1.5/1.25 3/ 1.25 = 1.2mg to 2.4mg Methylprednisolone 4mg tablets: Give tablet once daily for ___ days then taper

More recently, the use of IPI504 (Retaspimycin, a synthetic derivative of Geldanamycin), in an in vitro model of age-related macular degeneration (AMD) on senescent ARPE-19 (human arising retinal pigment epithelial cells), leads to a decrease of SA--Galactosidase positive cells, associated with a downregulation of senescence-associated gene expression as well as SASPs secretion, suggesting that in some cases HSP90 inhibitors could also be used as senomorphics 27