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SKU: 23102567472
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However, in humans, proline has been known to be catalyzed by proline oxidase (POX), being regulated by age or by the peroxisome proliferator-activated receptor gamma (PPAR) regulator [132,133,134,135]

Clinical pharmacology and therapeutics, 17 (5), 534540

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Immune effects are restorative, not overstimulating: It rebalances T-cell ratios, upregulates IL-2 in aged tissues, and improves neuroimmune integration, suggesting a targeted recalibration of immune tone rather than indiscriminate boosting. It restores circadian and hormonal rhythms: By stimulating melatonin synthesis, protecting pineal structure, and re-entraining clock genes, Epitalon may counter the widespread circadian drift of aging, with implications far beyond sleep, touching immunity, metabolism, and neuroprotection