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Hosein et al., 2012) didnt display any toxicity profile related to renal dysfunction at dose-limiting toxicity (DLT)

However, the clinical translation of free DFO is hampered by its unfavorable pharmacokinetics and safety profile, including a short plasma half-life, low bioavailability, poor blood-brain barrier penetration, and potential severe adverse effects upon long-term use (Lei et al., 2024)

Depending on the patient, a healthcare professional may consider: Pulse wave velocity is not a blood test, but it can provide physiologic information about arterial stiffness