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287 Increasing preclinical and clinical evidence suggests that TGF- signaling activation in established anti-cancer therapies such as targeted therapies, chemotherapy, and radiation is a driver of drug resistance, 288,289 involving multiple mechanisms such as induction of EMT, metabolic reprogramming, activation of alternative pathways, promotion of an immune-suppressive microenvironment, induction of a stem cell-like phenotype, and promotion of drug uptake and efflux

Yet another study confirmed the positive antioxidative and analgesic effect of curcumin as compared with treatment using propranolol and indomethacin [68] (Table 2)

SotkMRajanMRClarkMBirserudCWalleniusVHagbergCEet alHealthy subcutaneous and omental adipose tissue is associated with high expression of extracellular matrix components

A combination of single residue resolution level NMR spectroscopy and truncated versions of -synuclein mutants have revealed the binding sites of zinc