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Hum Ecol Risk Assess Int J

Anqi L, Ziying S, Xingquan X, Sheng Z, Jiawei L, Heng S, Quan W, Qing J, Hui W, Dongquan S

While considerable efforts have been directed toward understanding the peripheral mechanisms of CIPN, emerging evidence indicates that CIPN-causing agents also induce changes in CNS neurons, leading to the development of central sensitization (Figure 2E)