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The current evidence base supports the idea that multi-pronged therapies targeting cellular metabolism, inflammation, and vitamin metabolism simultaneously have the greatest potential for translating into effective treatments for ASD

Accordingly, the present review examines current evidence on mitochondriaorganelle interactions in pancreatic acinar cells and considers how an integrated intracellular network perspective may deepen understanding of AP pathogenesis and support future progress in biomarker research and therapeutic strategy development

Abstract Nuclear factor erythroid 2-related factor 2 (NRF2) is a stress responsive transcription factor that is mutationally activated in a subset (~25%) of clinically-aggressive non-small cell lung cancers (NSCLC)