This antioxidant is a fatty acid which is found within the mitochondria of cells
Jacobs PL, et al
The reported incidence for myocarditis with clozapine is 0.015%8.5%, and that for olanzapine is 0.002%, risperidone is 0.002%, and that for quetiapine is 0.006%.[] In terms of geographical variation, higher incidence of clozapine-associated myocarditis has been reported in people from Australia.[] Clozapine-associated myocarditis has maximum level of evidence, compared to myocarditis associated with other psychotropics and it is suggested to be due to immunoglobulin Emediated hypersensitivity reaction.[] It is usually seen during the initial part of the treatment (first 23 months) with clozapine in previously healthy adults, with some cases reported as late as 1 year.[] The dose range associated with myocarditis has varied from 50 to 600 mg/day with a median dose of 250 mg/day.[] Various risk factors associated with clozapine-associated myocarditis include rapid increase in dose, increasing age, concomitant use of sodium valproate, SSRIs, lithium, another SGA, obesity, higher body-mass index, and increased serum concentration of creatine kinase.[] The clinical presentation of myocarditis could be variable and it may manifest with nonspecific symptoms such as fever, flu-like symptoms, nausea, and dizziness
The marginal branch of the mandible of the facial nerve was delimited in order to avoid injection in this area, thus preventing possible damage to the nerve [16]
