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Because adenosine plays a critical role in the control of sleep-wakefulness (Thakkar et al., 2003), and chronic alcoholism is frequently accompanied by sleep disorders (Brower, 2001), changes in sleep pattern may also induce alteration in gliotransmitter release

However, hesperidin has been reported to attenuate ironinduced decline in glutathione-s-transferase activity in rat liver earlier [77] Catalase or oxidoreductase (EC

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