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Establishment of the TXNIP-overexpressing diabetic animal model C57BL/6, male mice were used in healthy mouse experiments or were rendered diabetic by multiple low-dose streptozotocin (STZ) injections (3 days

Issues such as low aqueous solubility, batch-to-batch variability of botanical extracts, and the absence of robust pharmacokinetic and pharmacodynamic data in humans continue to limit their direct comparability with synthetic agents [37,38,39]