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As always, patch test first and follow the product's specific usage instructions

The observation that higher plasma concentrations of 2 can be achieved after oral delivery than for PZQ, coupled with the greater ex vivo potency of compound 2 , strongly suggest that further optimization will yield an orally bioavailable schistosomicidal agent that will be transformative in the clinical setting

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They are the enzymes that make up pathways for energy metabolism, cellular growth, signaling, mitotic cycle and cell death