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For additional information regarding the policy finalized for CY 2025, reference 89 FR 93948 through 93963

This contrasts with observations from various other tissues and cells exposed to high glucose levels in vitro, typically within the 20 mM to 30 mM range, where chronic exposure (e.g., in podocytes, endothelial cells, myotubes, epithelial cells, pancreatic cells, and aortic tissues) often resulted in basal respiration rates that either remained unchanged or were reduced (Audzeyenka et al

10.1136/ard-2023-224032 96 Perez-GarciaL