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This time the deletions are internal deletions so that there are no bases on the 5 or 3 of the subject sequence which are not matched/aligned with the query

Excessive alcohol consumption results in a range of alcoholic liver disease (ALD), from simple alcoholic fatty liver to advanced alcoholic hepatitis, cirrhosis, and eventually hepatocellular carcinoma [2]

74 It is unclear, however, whether high doses of ESA are inherently toxic or whether hyporesponsiveness is a marker of adverse outcomes related to co-morbidities

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