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2) Nonoxidative steps of pentose phosphate shunt transketolase requires thiamine pyrophosphate (vitamin B1) transketolase requires thiamine pyrophosphate (vitamin B1) Positive regulator of lipid synthesis GSSG is oxidized and GSH is reduced glutathione

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Carthamin yellow mitigated the effects of MCAO-induced ferroptosis by reducing iron and ROS accumulation, decreasing LPO, and restoring the expression levels of proteins linked to ferroptosis ( 2+ and ROS and restored the levels of ACSL4, TFR1, GPX4, and FTH1 proteins in the brain ( 5.3 Polyphenols Polyphenols are formed by direct connection between hydroxyl (-OH) groups and aromatic nuclei (benzene rings or condensed benzene rings)

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