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A randomized controlled trial of oral crocin from saffron (30 mg/day) versus placebo for eight weeks in 177 cancer patients who had been experiencing symptoms of CIPN for at least a month reported that patients who received saffron tablets had lower levels of sensory, motor, and neuropathic pain, with similar side effects to placebo (Bozorgi 2021)

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In the management of weight, inositol, when used in combination with other B complex vitamins, helps the liver break down fats in the body, and when used in combination with other compounds in a MIC injection, especially choline, inositol forms lecithin which is known to aid in the metabolism of fat