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The most common include mild tenderness or redness at the injection site, a temporary flushed or warm feeling from the B vitamins, and occasional mild nausea or diarrhea

The following table summarizes common claims and their evidence basis: The key pattern: most benefits are real only for individuals who are actually deficient in B12

Always refer to the ingredient list on the product label before use.

From a translational perspective, the question remains if and how the intradiscal implantation of MSCs (whether or not delivered using a carrier) in chronic degenerated discs will result in the inhibition of neurite ingrowth into the disc and pain relief