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Moreover, the severity of IL-1-induced joint degradation in TLR4 -/- mice was reduced, with similar levels of inflammation, suggesting independent processes (175)

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J Contemp Dent Pract 19(2):137142

The critical role of atypical protein kinase C in activating hepatic SREBP-1c and NFkappaB in obesity

Increasing TMAO concentrations downregulated APOA4 expression and upregulated PCSK9 expression, demonstrating a concentration-dependent effect of TMAO on both APOA4 and PCSK9 (Supplementary Fig