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While the [U- 13 C]serine tracing showed SAAR increased labeling of other fates of cysteine such as taurine, loss of hepatic PSAT1 uniquely attenuated the increased liver 13 C-GSH and 13 C-GSSG from [U- 13 C]glucose

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These findings suggest that C10:2 may serve as a potential biomarker for PH diagnosis and provide a foundation for the development of novel anti-PH therapeutic strategies

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