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Selenium, Antioxidants, and Thyroid Health CHRIS MASTERJOHN: And then there are other things, too

A second mutation (G482A), which is also associated with this disorder, introduces a Pst1 site with decreased enzyme capacity [45]

Folinic acid (5-formyltetrahydrofolate) was selected in light of the fact that it is absorbed as the reduced metabolite is rapidly polyglutamated and is more readily available for folate-dependent reactions than the synthetic vitamin form of folic acid