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The C-terminal domain contributes, together with the N-terminal domain, to shaping the co-substrate binding site, which is termed H-site, from the hydrophobic nature of co-substrates

When ERAD capacity is overwhelmed or dysfunctional, unresolved ER stress ensues, driving metabolic dysregulation and disease progression (Fig

Some of the tools clinicians use to diagnose OCD include: Y-BOCS (Yale-Brown Obsessive-Compulsive Scale) considered the gold standard for measuring OCD severity, says Delventhal

Kalynchuk, [email protected] This article was submitted to Neurodegeneration, a section of the journal Frontiers in Neuroscience Disclaimer All claims expressed in this article are solely those of the authors and do not necessarily represent those of their affiliated organizations, or those of the publisher, the editors and the reviewers