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Proponents of B12 shots state that they turbocharge the metabolism (make you thinner), strengthen the immune system, and help cure fatigue, insomnia, and even depression

We note that, for cases in which a recommendation by the HOP Panel appears to result in or allow a violation of the 2 times rule, we generally accept the HOP Panel's recommendation because those recommendations are based on explicit consideration of resource use, clinical homogeneity, site of service, and the quality of the claims data used to determine the APC payment rates