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However, the specific molecular pathways through which these variations impact disease onset and progression remain unclear

The information of the admitted patients was obtained from the minimum basic set of hospital discharge data

One of the first lines of evidence of this interaction was obtained in a series of experiments showing the hyperalgesic actions of this peptide

These kinases phosphorylate the membrane transporters (DAT, NET, SERT), leading to two outcomes: the transporters are either internalized into the cell (ceasing all reuptake function) or they undergo a conformational shift that causes them to operate in reverse