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Notably, cholinergic neurons in the basal forebrain bundle are distorted in AD, leading to memory loss and impaired cognition (Lin et al., 2022)

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[123] reported that the RNA silencing mechanism occurs at least three different levels in plants, including cytoplasmic silencing using dsRNA resulting in mRNA cleavage,endogenous mRNAs silenced by miRNAs regulating gene expression, leading to RNA degradation or translational protein inhibition known as PTGS