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Am J Hypertens 27(3):460470

While Lewy-bodies appear to trigger cell death by blocking intracellular-transport as well as impairing mitochondrial and synaptic function, they may develop in response to sequestration of aSyn oligomers that are highly toxic

Without sufficient carnitine, fatty acids cannot efficiently enter the mitochondria (even if there are abundant fat stores)

In addition, Wt+R mice had a significantly ( p = 0.04) higher normalized expression of Cd68 in the midbrain (1.22 0.06 SEM) compared to Wt+V (1 0.02 SEM)