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Furthermore, Ca 2+ -dependent C2 membrane binding disrupts C2/HECT interactions, but not Ca 2+ alone, whereas 14-3-3 protein binds to a flexible region of Nedd4-2 containing the WW2 and WW3 domains, thereby inhibiting its catalytic activity and membrane binding

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The swelling of mitochondria, the dilatation of intercellular space and the dilatation of inner plasma can be seen clearly in electron microscope (9)

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NPs can cause increased oxidative stress through inflammation and produce surface radicals (91, 92)

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Gallo called the virus "human T-lymphotropic virus type III" (HTLV-III) because of perceived similarities with HTLV-I and -II, which had previously been discovered in his lab

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