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ISF-based sensing must contend with lower analyte concentrations, depth-dependent variability, biofouling, and long-term signal drift

[DOI] [PMC free article] [PubMed] [Google Scholar] 231.Hagar H.H

In contrast, in the presence of Pi, substrate binding was equal and independent, with the enzyme subunits forming symmetrical tetramers in the X-ray crystal structures [18]