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While the glycolytic glucose metabolism and the mitochondrial oxidation of glycolysis-derived pyruvate and amino acid-derived -keto acids have been extensively studied for astrocytes, more information is warranted to understand the contribution of LDs [189, 190] and proline [70, 257] in the energy metabolism of astrocytes, especially considering the known consequences of alterations in the metabolism of LDs [190, 258] and proline [259] in human neurological diseases

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Combined Donepezil with Astaxanthin via Nanostructured Lipid Carriers Effective Delivery to Brain for Alzheimers Disease in Rat Model