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This paper combines the unbiased identification of gene fusions with unsupervised gene expression analyses to identify biologically homogeneous groups of tumours including CIC -rearranged, BCOR -rearranged and EWSR1 NFATC2 or FUS NFATC2 sarcomas

Lipid and vitamin metabolism pathways, including thiamine, biotin and lipoic acid, were also downregulated in GLI, mirroring transcriptomic data (Loberman-Nachum et al, 2019)

PMID 15643610

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