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c-di-GMP signalling and the regulation of developmental transitions in streptomycetes

Oral formulations have been investigated for their potential effects on the stomach, intestines, and gastrointestinal lining while also being evaluated for broader systemic activity

These include approved prescription weight-loss medications based on synthetic peptides that mimic natural hormones, such as semaglutide and tirzepatide, found in weight loss drugs such as Wegovy and Mounjaro respectively

Although the exact physiological role remains under study, DSIP has been associated with modulation of hypothalamic and pituitary activity in experimental models