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This activation contributed to the acquisition of stem-like features and promotes therapeutic resistance ( FIGURE 4 4.2 Upregulation of ATP-binding cassette (ABC) transporters and drug efflux Overexpression of ATP-binding cassette (ABC) transporters actively expels therapeutic agents from cancer cells (Zhong et al., 2024)

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Also, other researchers have measured decreased SOD activity in the lenses of patients with senile and diabetic cataract 66

Kinetic and pharmacological properties of GABA(A) receptors in single thalamic neurons and GABA(A) subunit expression