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Injectable B12 has few direct drug interactions, but certain medications can interfere with B12 absorption or measurement: Chloramphenicol: This antibiotic may antagonise the haematological response to B12 in some patients, potentially preventing the expected rise in red blood cell count

Bioavailability between SubQ and IM routes for small peptides like 5-Amino-1MQ differs by less than 8% in comparative pharmacokinetic studies, meaning the practical advantages of SubQ outweigh any marginal uptake differences

Johnson T, Kang D, Barnard E, Li H

Discovery of Bisubstrate Inhibitors of Nicotinamide N-Methyltransferase (NNMT)