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Activated mast cells can trigger microglial activation via the release of histamine, prostaglandins, and protease-activated receptor ligands (Zhang et al., 2016)

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138-142 9 Dietary And Lifestyle Considerations Diet A low-sodium diet is a commonly used management strategy for Mnire disease, as is avoidance of caffeine, although conclusive evidence from rigorous controlled trials is still lacking for these interventions