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The Journal of endocrinology , 165 (3), 569577.

Why pulsatile GH release outperforms supraphysiological dosing Exogenous HGH raises circulating GH in a flat, non-pulsatile pattern that the body has not evolved to process

Enhanced Muscle Growth and Recovery Promotes Protein Synthesis : IGF-1 LR3 stimulates the synthesis of new proteins in muscle tissue, aiding in hypertrophy (muscle growth)