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Understanding the complex absorption process of vitamin B12 helps explain why some individuals develop deficiency despite adequate dietary intake, and why different supplementation strategies may be necessary for different people

Mandal PK, Rossi DJ

Clinical Pharmacology for Nascobal General Pharmacology And Mechanism Of Action Vitamin B 12 is essential to growth, cell reproduction, hematopoiesis, and nucleoprotein and myelin synthesis

For the reasons presented in the sections above, this approach would exclude a significant fraction of patients for which serum vitamin B 12 does not reflect cellular, genetic, and pharmacological disturbances that lead to functional vitamin B 12 deficiency