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7,8,64 NAMPT facilitates increases in CSC pools, suggesting that the CSCs in tumors primarily use the NAD salvage pathway to maintain a full, rich source of nutrients for enzymatic activity, leading to tumor progression and the eventual reprogramming of mature tumor cells, which finally results in therapy resistance, relapse, and metastasis

(2003) MtDNA mutations in aging and apoptosis

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105 Ozagrel hydrochloride also significantly reduced hepatocyte death by downregulating CHOP expression