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In a PCPA-induced insomnia mouse model, DSIP-CBBBP outperformed DSIP alonemore effectively restoring neurotransmitter balance, reducing wakefulness, easing anxiety and depression-like behaviors, improving reward response, and repairing brain tissue damage

Janarny et al

When compared with the other H 2 O 2 scavenger enzymes, CAT seems to be the key enzyme to remove high intracellular concentrations of H 2 O 2 [32, 53, 59, 60]

Ferroptosis of retinal cells, such as RPE, photoreceptor, and RGC, has been reported to be involved in the progression of age-related/inherited macular degeneration, blue light-induced retinal degeneration, glaucoma, DR, and retinal damage caused by retinal IR via multiple molecular mechanisms