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Huang R, Wang HHJ, Huang O,He JCW, Li Y, Chen XSK, Wang Z

Data on new targeted therapies are even more promising: vedolizumab, as a gut-specific anti-integrin, has demonstrated a rare incidence of severe adverse events in registered trials, open extensions, and real-world data, while remaining safe in pregnant patients, children, the elderly, and those with a history of cancer [334]

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The expression levels of HIF-1 were reduced following the overexpression of SIRT4