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Intrathecal injection of HVJ-E containing HGF gene to cerebrospinal fluid can prevent and ameliorate hearing impairment in rats

This format provides a convenient research tool for investigations involving comparative peptide pharmacology, concurrent evaluation of multiple signaling mechanisms, and studies examining interactions between distinct peptide-associated regulatory pathways

It is analyzed using HPLC and LC-MS

emission 520 nm) was read in the upper and lower chambers, and the permeability coefficient was determined using the following formula: 22 P dextran =( RFU lower / RFU upper )( V )(1/ t )(1/ A ), where RFU is the relative fluorescent units in the upper and lower wells, V is the volume of the bottom well, t is the time that the FITC-dextran was allowed to diffuse, and A is the total surface area of the monolayer (cm 2 )