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Despite some reports on the similarities between senescence and eryptosis at the morphological level [67], intracellular Ca 2+ elevation [74], Ca 2+ -driven activation of Gardos channels [70], PS exposure [76], or ROS contribution [71], senescence of erythrocytes cannot be considered an RCD of these cells and should be clearly distinguished from eryptosis

Radioactive iodine therapy serves as a viable alternative to surgery but necessitates extended hospitalization and clinical follow-up post-treatment (Slonimsky and Tulchinsky 2020)

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In contrast, only limited evidence exists for MT3 in MS with mRNA levels being unchanged in EAE mice and decreased in the human grey matter 16