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Often it is gradual: less energy, longer recovery, worse sleep, or difficulty maintaining lean muscle

After the rebound of 2023, this steady growth signals continued recovery across the global R&D landscape

Importantly, we evaluate recent potential therapeutic targets and promising interventions, providing guidance for future targeted treatment therapies against human diseases

The aetiology of HS is complex and multifactorial, involving genetic predisposition, environmental triggers like smoking, and significant systemic comorbidities, including metabolic, cardiovascular, musculoskeletal, gastrointestinal, and mood disorders