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Duas revises sistemticas ( Brando et al., Porto Biomedical Journal, 2021, e Osadchiy et al., Current Sexual Health Reports, 2020 ) confirmam o padro: o Lactobacillus aparece de forma consistente associado a parmetros seminais normais, enquanto gneros como Anaerococcus se associam a pior qualidade espermtica, embora ambas reconheam que a rea ainda tem heterogeneidade metodolgica e necessita de mais estudos prospectivos de larga escala

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Patients with Fabry disease experience peripheral neuropathy, sensory abnormalities, acute pain crises, and lifelong ongoing pain [82]

Using genetic proxies for l-carnitine minimizes confounding, which is challenging in observational studies