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It's grassroots

Prevention of allergic disease in childhood: Clinical and epidemiological aspects of primary and secondary allergy prevention

That poses a public health threat

While AOPs provide a structured representation of biological mechanisms from an MIE to an AO, AEPs describe the progression of a stressor from its environmental source to the site of internal exposure, situated upstream of the AOPs MIE ( Here, we propose the first fully computational workflow that combines automated literature mining and machine learning with established AOP and AEP frameworks to investigate how co-exposure to radon and tobacco smoke contributes to lung cancer