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Together, these results support the hypothesis that cysteine derived from lysosomal cystine efflux limits the activity of the -glutamyl cycle and GSH synthesis

2022 Jan 17;2022:8038857

Subsequently, it remotely activates alveolar macrophages, promotes the formation of neutrophil extracellular traps, and disrupts the balance of regulatory T cells/Th17 cells, ultimately exacerbating lung injury