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In our previous studies, we demonstrated that TGP intervention could regulates intestinal microbial imbalance, Th1/Th2 and Th17/Treg ratio imbalance in peripheral blood and inhibits intestinal cytokines SIgA and IFN- in CIA rats (Peng et al., 2019)

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conversely, inhibiting either SHMT1 or SHMT2 induces ROS accumulation and impairs the survival of KLK NSCLC (KEAP1: KLK oncogenotype) [12]

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