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Key Points Ghrelin is a hormone secreted mainly from the stomach into the circulation Ghrelin stimulates growth-hormone release Ghrelin stimulates appetite and increases food intake Ghrelin is useful for treatment of weight loss and eating disorders Gastric bypass decreases ghrelin levels and leads to weight loss Ghrelin improves cardiovascular function This is a preview of subscription content, access via your institution Access options Subscribe to this journal Receive 12 print issues and online access $189.00 per year only $15.75 per issue Buy this article Purchase on SpringerLink Instant access to the full article PDF