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The definition of moderate certainly is that we are moderately confident in the effect estimate (the true effect is likely to be close to the estimate of the effect, but there is a possibility that it is substantially different)

Dopaminergic neurons in the substantia nigra , the brain region most affected by Parkinson's disease, express receptors for an inflammatory cytokine called tumor necrosis factor-alpha (TNF-) , which suggests that excess TNF- released by nearby activated microglia may damage nigral dopaminergic cells

We also go beyond FDA requirements by testing for additional bacteria, including Listeria monocytogenes, Bacillus cereus, and Staphylococcus aureus