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Ryan JJ, Klein KA, Neuberger TJ, Leftwich JA, Westin EH, Kauma S, et al

L-carnitine IV therapy is generally safe when administered by qualified healthcare professionals

Characterized by motor deficits and cognitive decline with some psychiatric symptoms such as depression and anxiety, HD is mainly due to abnormal duplication of CAG nucleotides of the gene encoding the Huntington protein, which eventually produces abnormal protein polyglutamine (polyQ) and largely accumulates in the neurons of basal ganglia (caudate-putamen), and finally cortico-striatal dysfunction